OUR TECHNOLOGY

Pioneering ex-vivo genome editing of organs on perfusion pumps

1.

2.

CRISPR Delivery

Our proprietary CRISPR components are delivered to the organ during perfusion window

3.

Precision Editing

Based on the applied platform, targeted genetic modifications are made while the organ is on pump

4.

How it works

Organ Recovery

Donor organs recovered by the OPO are placed on perfusion pumps

Enhanced Transplants

Optimized organs are transplanted with improved outcomes for the patients

Cas1x

Antiviral Platform

  • Eliminates CMV and BKV

  • Reduces infection risk

  • One-shot treatment

  • Completely ex vivo

CasNx Platforms

Cas2x

  • Removes HLA antigen

  • Universal Compatibility

  • Reduced organ wastage

Universal Organs

Genome editing organs on the pump

Cas3x

  • Reduces rejection

  • Cytoprotective genes

  • Extended graft lifespan

Longevity Platform